Lista de publicaciones

Artículos científicos 

Las publicaciones de Paola Andrea Acosta Guzmán corresponden a trabajos de investigación en el área de las ciencias químicas, desarrollados principalmente en química orgánica y enfocados en la síntesis de moléculas con potencial actividad biológica. Estos estudios se han realizado en el marco de proyectos de investigación académica y han contribuido al avance del conocimiento en esta área.

1. Organocatalytic Halogenation of Aromatic and Heteroaromatic Compounds

P Acosta‐Guzmán, A Garay‐Talero, D Gamba‐Sánchez

European Journal of Organic Chemistry 2025, 28, e202500125.

2. Design and Evaluation of NSAID Derivatives as AKR1C3 Inhibitors for Breast Cancer Treatment through Computer-Aided Drug Design and In Vitro Analysis

V Fonseca-Benítez, P Acosta-Guzmán, JE Sánchez, Z Alarcón, Ronald Andrés Jiménez, James Guevara-Pulido

Molecules 2024, 29, 1802.

3. Synthesis of pyrimido[4,5-b]quinolindiones and formylation: ultrasonically assisted reactions

Jorge Trilleras, Andrés Charris-Molina, Alfredo Pérez-Gamboa, Paola Acosta-Guzman, Jairo Quiroga

Royal Society Open Science 2024, 11, 231128.

4. Modulation of TRPV1 on odontoblast-like cells using capsazepine-loaded nanogels

LJ Bernal-Cepeda, RA Jiménez, ML Velandia-Romero, P Acosta-Guzmán, , Jaime E Castellanos

Pharmaceutics 2024,16, 355.

5. Design and synthesis of a potential selective JAK-3 inhibitor for the treatment of rheumatoid arthritis using predictive QSAR models

M Prieto, A Niño, P Acosta-Guzmán, J Guevara-Pulido

Informatics in medicine unlocked 2024, 45, 101464.

6. Contemporary approaches for amide bond formation

P Acosta‐Guzmán, A Ojeda‐Porras, D Gamba‐Sánchez

Advanced Synthesis & Catalysis 2024, 365, 4359-4391

7. Regioselective Organocatalyzed Monochlorination of Arenes with Electrophilic Chlorosulfoniums

A Garay‐Talero, P Acosta‐Guzmán, D Gamba‐Sánchez

Advanced Synthesis & Catalysis 2023, 365, 4576-4582

8. Contemporary approaches for amide bond formation

P Acosta‐Guzmán, A Ojeda‐Porras, D Gamba‐Sánchez

Advanced Synthesis & Catalysis 2023, 365, 4359-4391.

9. Design, synthesis, and development of 4‐[(7‐Chloroquinoline‐4‐yl) amino] phenol as a potential SARS‐CoV‐2 mpro inhibitor

J Guevara‐Pulido, RA Jimenez, SJ Morantes, DN Jaramillo, Paola Acosta‐Guzmán

ChemistrySelect 2022,7, e202200125.

10. Contribución Latinoamericana a la exploración y aplicaciones de los procesos órgano-catalíticos

DJ Gutierrez, CM Manrique, PA Guzman, JOG Pulido

Avances en Química 2022, 17, 3-8

11. Electrophilic Chlorine from Chlorosulfonium Salts: A Highly Chemoselective Reduction of Sulfoxides

P Acosta‐Guzmán, C Mahecha‐Mahecha, D Gamba‐Sánchez

Chemistry–A European Journal 2022, 26, 10348-10354

12. Recent progress in the synthesis of naturally occurring siderophores

F Garzón‐Posse, Y Quevedo‐Acosta, C Mahecha‐Mahecha, Paola Acosta‐Guzmán

European Journal of Organic Chemistry 2019, 2028, 7747-7769

13. Pummerer synthesis of chromanes reveals a competition between cyclization and reductive chlorination

P Acosta-Guzman, A Rodriguez-Lopez, D Gamba-Sanchez

Organic Letters 2029, 21, 6903-6908

14. Direct transamidation reactions: mechanism and recent advances

P Acosta-Guzmán, A Mateus-Gómez, D Gamba-Sánchez

Molecules 2018, 23, 2382.

15. Synthesis of novel 7-aryl and 7-spiropyrazolo[4′,3′:5,6]pyrido[2,3-d]pyrimidine derivatives and their study as AChE inhibitors

P Acosta, B Insuasty, R Abonia, M Gutierrez, J Quiroga

Molecular Diversity 2017, 21, 943-955

16. Synthesis and study of the electronic properties of pyrazolo[1,5-c]pyrrolo[1,2-a]quinazoline and pyrazolo[1,5-c]pyrido[1,2-a]quinazoline derivatives

P Acosta, A Ortiz, B Insuasty, R Abonia, J Quiroga

Monatshefte für Chemie-Chemical Monthly 2017, 148, 237-244.

17. Solvent-free microwave-assisted synthesis of novel pyrazolo [4′, 3′: 5, 6] pyrido [2, 3-d] pyrimidines with potential antifungal activity

P Acosta, B Insuasty, A Ortiz, R Abonia, M Sortino, SA Zacchino,

Arabian Journal of Chemistry 2016, 9, 481-492.

18.Synthesis and study of fluorescence properties of novel pyrazolo [4′, 3′: 5, 6] pyrido [2, 3-d] pyrimidin-5 (6H)-one derivatives

J Quiroga, P Acosta, A Ortiz, B Insuasty, R Abonia

Journal of Molecular Structure 2017, 1097, 69-75.

19. Solvent-free microwave-assisted synthesis of novel pyrazolo [4′, 3′: 5, 6] pyrido [2, 3-d] pyrimidines with potential antifungal activity

P Acosta, B Insuasty, A Ortiz, R Abonia, M Sortino, SA Zacchino, Jairo Quiroga

Arabian Journal of Chemistry 2016, 9, 481-492.

20. Synthesis and study of fluorescence properties of novel pyrazolo [4′, 3′: 5, 6] pyrido [2, 3-d] pyrimidin-5 (6H)-one derivatives

J Quiroga, P Acosta, A Ortiz, B Insuasty, R Abonia

Journal of Molecular Structure 2015, 1097, 69-75.

21. Annelation of pyrrolo [1, 2-a] pyrimidine and pyrido [1, 2-a] pyrimidine systems to a pyrazolopyridine framework by a cascade of two cyclization reactions

P Acosta, B Insuasty, R Abonia, J Quiroga

Tetrahedron Letters 2015, 56, 2917-2921.

22. Exploiting the reactivity of 1, 2-ketoamides: Enantioselective synthesis of functionalized pyrrolidines and pyrrolo-1, 4-benzodiazepine-2, 5-diones

P Acosta, D Becerra, S Goudedranche, J Quiroga, T Constantieux, ...

Synlett 2015, 26, 1591-1595.

23. Microwave-Assisted Synthesis of Novel Pyrazolo[3,4-g][1,8]naphthyridin-5-amine with Potential Antifungal and Antitumor Activity

P Acosta, E Butassi, B Insuasty, A Ortiz, R Abonia, SA Zacchino, J Quiroga

Molecules 2015, 20, 8499-8520.

24. Microwave-assisted synthesis of fused pyrazolo [3, 4-b] pyrazines by the reaction of ortho-aminonitrosopyrazoles and cyclic β-diketones

J Quiroga, NE Sánchez, P Acosta, B Insuasty, R Abonia

Tetrahedron Letters 2012, 53, 3181-3187.

25. Annelation of pyrrolo [1, 2-a] pyrimidine and pyrido [1, 2-a] pyrimidine systems to a pyrazolopyridine framework by a cascade of two cyclization reactions

P Acosta, B Insuasty, R Abonia, J Quiroga

Tetrahedron Letters 2010, 56, 2917-2921.

Capitulos de libro

1. Transamidation of carboxamides and amide derivatives: mechanistic insights, concepts, and reactions

P Acosta‐Guzmán, J Corredor‐Barinas, D Gamba‐Sánchez

Amide Bond Activation: Concepts and Reactions, 187-219.

2. Greener Methods for Halogenation of Aromatic Compounds

P Acosta-Guzmán, D Gamba-Sánchez

Greener Synthesis of Organic Compounds, 41-56.

3. Microwave as a Greener Alternative in the Synthesis of Organic Compounds

P Acosta-Guzmán

Greener Synthesis of Organic Compounds, 57-73.